Real Madrid's Gareth Bale and Arsenal midfielder Aaron Ramsey will miss Wales' friendly at home to the Netherlands on November 13, manager Chris Coleman said on Wednesday.
Andy Carroll scored a eight-minute hat-trick as West Ham United's last London derby at Upton Park ended in a barnstorming 3-3 draw with Arsenal on Saturday -- a result that dented both club's respective ambitions.
"The best team won, we struggled from the beginning and we couldn't deal with their long balls. Usually, you press the ball to win it, but this was different. They defended so deep and so well," City coach Pep Guardiola told the BBC.
Liverpool moved to 76 points from 32 games with title rivals Manchester City on 74 points from one game fewer, with Pep Guardiola's side hosting Brighton and Hove Albion at the Etihad on Wednesday.
Chelsea beat Sheffield United 2-0 to reach the FA Cup semi-finals for the fourth time in five seasons.
Images from Sunday's action in the English Premier League.
A summary of Saturday's action in the Premier League.
IMAGES from the EPL matches played on Sunday.
A round-up of Saturday's action in the Nations League.
Saturday's 2-1 FA Cup quarter-final defeat at Wolverhampton Wanderers followed a 2-0 loss at Arsenal last week.
Among other transfer news globally, defender Rahul Bheke joins Mumbai City FC while Locatelli completes Juventus move.
United are four points behind fourth-placed Arsenal, with a game in hand, as they search for a way into the top four and a place in next season's Champions League.
Images from the English Premier League matches played on Sunday.
Aaron Ramsey's winning goal for Arsenal in their 3-2 FA Cup final victory against Hull City was a moment of sublime redemption for the player, his manager, his club and the old competition itself.
The two previous meetings at Anfield ended in 4-0 and 3-1 defeats for Arsene Wenger's Arsenal teams, but there is a fresh optimism around the club after a successful transfer window.
IMAGES from the English Premier League matches played on Saturday
Rangers joined Barca in the last eight despite losing 2-1 at Red Star Belgrade, progressing 3-2 on aggregate.
'It would be a bit ridiculous that 20 years depends on one game and that the future of the club depends on one game'
Goalkeeper De Gea was forced to leave the field during Spain's Euro 2020 qualifier against Sweden on Tuesday.
Arsene Wenger's final match at Old Trafford as Arsenal manager ended in defeat with a stoppage time header from substitute Marouane Fellaini earning the points for second-placed Manchester United.
Liverpool head to United with widest gulf in years
List of major transfers in the top Premier League ahead of the 2019-20 season (all transfer fees as reported by British media):
The bowling attack looks the most settled this year and if batting manages to compliment the bowling, RCB can expect to have a solid season.
Images from EPL matches played on Saturday.
Images from Saturday's action in the English Premier League
Aaron Ramsey, a player that Wales manager Chris Coleman believes has the talent to represent any international side, will start Saturday's World Cup Group D qualifier against Serbia in Cardiff.
Liverpool moved into the Champions League qualifying spots after a 3-0 win at Burnley on Wednesday took them above Leicester City and into fourth place with one round of Premier League matches remaining.
Arsenal midfielder Aaron Ramsey has suffered a setback in his recovery from a thigh injury, manager Arsene Wenger said on Tuesday.
Stoke City defender Ryan Shawcross was called into the England squad for the first time on Saturday, hours after he had been sent off for a challenge that left Arsenal's Aaron Ramsey with a serious leg injury.
De Rossi, who turned 36 on Wednesday, led Roma for the final time in a 2-1 victory over Parma at the Stadio Olimpico in May and finished his stint in the Italian capital with 616 appearances in 18 years.
Images from Saturday's action in the English Premier League.
Arsenal midfielder Aaron Ramsey says he has yet to reach an agreement with the Premier League club about his future. The Wales international, who joined the club in 2008, is in the final year of his contract.
Arsenal manager Arsene Wenger has risked angering frustrated fans by saying the under-performing London club do not need any January signings if everyone in the current squad stays fit.
IMAGES from the English Premier League matches played on Sunday
Cech's solid 'keeping and Liverpool's staunch defence ensured the match ended in a goalless stalemate
'Barcelona are super favourites for this game and tomorrow everyone is already convinced that we have to be totally focused as a whole squad'
Images from the English Premier League matches played on Sunday.
With United unable to sign a replacement, the pressure will be on 21-year-old England forward Marcus Rashford to deliver the goals in a more central role than he has previously operated in.
News of all that's transpired on and off the football field
However, one goal proved enough for City who picked up their sixth successive league win to move four points clear of Liverpool, who host Aston Villa later on Saturday, at the top of the standings.